• Algebraic Reasoning About Timeliness 

      Haeri, Seyed Hossein; Thompson, Peter W; Van Roy, Peter; Haveraaen, Magne; Davies, Neil J; Barash, Mikhail; Hammond, Kevin; Chapman, James (Journal article; Peer reviewed, 2023)
      Designing distributed systems to have predictable performance under high load is difficult because of resource exhaustion, non-linearity, and stochastic behaviour. Timeliness, i.e., delivering results within defined time ...
    • Mind Your Outcomes: The ∆QSD Paradigm for Quality-Centric Systems Development and Its Application to a Blockchain Case Study 

      Haeri, Seyed Hossein; Thompson, Peter; Davies, Neil; Van Roy, Peter; Hammond, Kevin; Chapman, James (Journal article; Peer reviewed, 2022)
      This paper directly addresses a long-standing issue that affects the development of many complex distributed software systems: how to establish quickly, cheaply, and reliably whether they can deliver their intended performance ...
    • Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner 

      Lagnado, Anthony; Leslie, Jack; Ruchaud-Sparagano, Marie-Helene; Victorelli, Stella; Hirsova, Petra; Ogrodnik, Mikolaj; Collins, Amy L; Vizioli, Maria Grazia; Habiballa, Leena; Saretzki, Gabriele; Evans, Shane A; Salmonowicz, Hanna; Hruby, Adam; Geh, Daniel; Pavelko, Kevin D; Dolan, David William Peter; Reeves, Helen L; Grellscheid, Sushma Nagaraja; Wilson, Colin H; Pandanaboyana, Sanjay; Doolittle, Madison; von Zglinicki, Thomas; Oakley, Fiona; Gallage, Suchira; Wilson, Caroline L; Birch, Jodie; Carroll, Bernadette; Chapman, James; Heikenwalder, Mathias; Neretti, Nicola; Khosla, Sundeep; Masuda, Claudio Akio; Tchkonia, Tamar; Kirkland, James L; Jurk, Diana; Mann, Derek A.; Passos, João F (Journal article; Peer reviewed, 2021)
      Cellular senescence is characterized by an irreversible cell cycle arrest as well as a pro-inflammatory phenotype, thought to contribute to aging and age-related diseases. Neutrophils have essential roles in inflammatory ...